beta-2 Microglobulin antibody (FITC)

Catalog No. ABIN112399

This Mouse Monoclonal antibody specifically detects beta-2 Microglobulin in WB, FACS, IP, IHC (p), RIA and EIA. It exhibits reactivity toward Human.

Quick Overview for beta-2 Microglobulin antibody (FITC) (ABIN112399)

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta-2 Microglobulin antibody is conjugated to FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), Enzyme Immunoassay (EIA)

Clone: B2M-01

Product Details anti-beta-2 Microglobulin Antibody (FITC)

Specificity: The antibody reacts with beta2-Microglobulin associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-Microglobulin.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Immunogen: Purified Human beta2-Microglobulin.

Isotype: IgG2a

Application Details

Application Notes: Immunfluorescence. Flow Cytometry (1/200).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: This product is photosensitive and should be protected from light

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Alternative Name: beta-2-Microglobulin

Background: B2M non-covalently associates with the 44 kDa alpha chain to forms the HLA Class I antigen complex. Human beta2-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes.Synonyms: B2M, Beta 2 microglobulin, Beta-2 microglobulin

Gene ID: 567

NCBI Accession: NP_004039

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process